The Guarded Domains of Iran, commonly called Safavid Iran, Safavid Persia or the Safavid Empire, was one of the largest and longest-lasting Iranian empires. It was ruled by the Safavid dynasty from 1501 to 1736, albeit others place the end on the year 1722, when Isfahan fell to the Afghans. It is often considered the beginning of modern Iranian history, as well as one of the gunpowder empires.