Hellenistic Greece is the historical period of Ancient Greece following Classical Greece and between the death of Alexander the Great in 323 BC and the annexation of the classical Greek Achaean League heartlands by the Roman Republic. This culminated at the Battle of Corinth in 146 BC, a crushing Roman victory in the Peloponnese that led to the destruction of Corinth and ushered in the period of Roman Greece. Hellenistic Greece's definitive end was with the Battle of Actium in 31 BC, when Octavian defeated Ptolemaic queen Cleopatra VII and Mark Antony, the next year taking over Alexandria, the last great center of Hellenistic Greece.