The Molossians were a group of ancient Greek tribes which inhabited the region of Epirus in classical antiquity. Together with the Chaonians and the Thesprotians, they formed the main tribal groupings of the northwestern Greek group. On their northern frontier, they neighbored the Chaonians and on their southern frontier neighbored the kingdom of the Thesprotians. They formed their own state around 370 BC and were part of the League of Epirus. The most famous Molossian ruler was Pyrrhus of Epirus, considered one of the greatest generals of antiquity. The Molossians sided with the Macedonians against Rome in the Third Macedonian War and were defeated. Following the war, the region witnessed devastation while a considerable number of Molossians and other Epirotes were enslaved and transported to the Roman Republic, in the Italian Peninsula.