The Macedonian Wars were a series of conflicts fought by the Roman Republic and its Greek allies in the eastern Mediterranean against several different major Greek kingdoms. They resulted in Roman control or influence over Greece and the rest of the eastern Mediterranean basin, in addition to their hegemony in the western Mediterranean after the Punic Wars. Traditionally, the "Macedonian Wars" include the four wars with Macedonia, in addition to one war with the Seleucid Empire, and a final minor war with the Achaean League. The most significant war was fought with the Seleucid Empire, and both this and the wars with Macedonia effectively marked the end of these empires as major world powers, even though neither of them led immediately to overt Roman domination. Four separate wars were fought against the weaker power, Macedonia, due to its geographic proximity to Rome, though the last two of these wars were against haphazard insurrections rather than powerful armies. Roman influence gradually dissolved Macedonian independence and digested it into what was becoming a leading empire.