Italy has been inhabited by humans since the Paleolithic. During antiquity, there were many peoples in the Italian peninsula, including Etruscans, Latins, Samnites, Umbri, Cisalpine Gauls, Greeks in Magna Graecia and others. Most significantly, Italy was the cradle of the Roman civilization. Rome was founded as a kingdom in 753 BC and became a republic in 509 BC. The Roman Republic then unified Italy forming a confederation of the Italic peoples and rose to dominate Western Europe, Northern Africa, and the Near East. The Roman Empire, established in 27 BC, ruled the Mediterranean region for centuries, contributing to the development of Western culture, philosophy, science and art.