Descartes is a large village and commune in the Indre-et-Loire department in central France. It is approximately 29 kilometers east of Richelieu and about 48 kilometers east of Loudun, on the banks of the Creuse River, near the border of the French department of Vienne, and the border of the region between Centre-Val de Loire and Nouvelle-Aquitaine. It is famous for the birthplace of the French mathematician and philosopher who invented the Cartesian coordinate system, René Descartes.